The results demonstrated that under physiological condition, RAGE was serine phosphorylated, while the serine phosphorylation of RAGE markedly decreased after cell stimulation by AGE in comparison to the unstimulated cells. 结果表明,在细胞生理状态下RAGE是受到丝氨酸磷酸化修饰的,受到AGE刺激以后,RAGE的丝氨酸磷酸化程度较静息状态下减弱。
The phosphoryl group in phosphorylated P21 was attached to the serine hydroxyl group and no phosphotyrosine and phosphothreonine were detected. 磷酸化21的磷酸根接在丝氨酸羟基,PP21不含磷酸酪氨酸或磷酸苏氨酸,或含量极微。