Aim To evaluate inhibitory effects of vinflunine on cellular microtubule assembly, and antitumor effects of vinflunine in vitro and in vivo. 目的检测长春氟宁(VFL)对微管聚集的作用,并研究长春氟宁(VFL)体外和体内的抗肿瘤作用。
Determination of vinflunine in Beagle dog ′ s plasma by LC-MS and study of its pharmacokinetics LC-MS法测定比格犬血浆中长春氟宁(VFL)浓度及其药代动力学