In all 9 hepatocellular carcinoma tissues, the positive expression of vitamin D receptor mRNA were detected. 9例肝癌组织标本维生素D3受体(VDR)mRNA表达均为阳性。
Objective : To construct an expression vector containing RNA interfering ( RNAi ) sequence targeting human vitamin D_3 receptor ( VDR ) protein gene, and to investigate its inhibitory effect on the expression and function of VDR in a human osteosarcoma cell line. 目的:构建由载体介导的抑制人维生素D3受体(VDR)(VDR)表达的RNA干扰载体,并在人骨肉瘤细胞中初步研究其对VDR表达及功能的影响。