Construction and Nucleotide Sequence Assay of Human Anti-HBs Variable Region Single Chain Antibody Gene 人源性抗HBs可变区单链抗体基因的构建及核酸序列测定
CONCLUSION : The light and heavy chain variable gene fragments of mouse anti-HBV-PT antibody are successfully cloned and expressed. These variable gene fragments of the antibody can be used for further immunotherapy studies of HBV infected patients. 结论:抗HBV末端蛋白轻、重链可变区基因的克隆及表达为进一步探讨HBV感染患者的免疫治疗奠定了基础。
Conclusion : We have successfully cloned light chain and heavy chain variable region gene of anti - TM-TNF - α monoclonal antibody C1, which is confirmed to be a new pair of functional rearranged variable region gene by immunoglobulin sequence analysis. 结论:成功克隆抗跨膜TNF-?单克隆抗体C1轻链及重链可变区基因,经序列分析证明为一对功能性免疫球蛋白可变区基因。
Cloning and Sequencing of Variable Region Genes of Rat Monoclonal Antibody Against HTV, Expression of Rat-human Chimeric Heavy Chain Antibody Specific for HTV in Mouse Myeloma Cell and Construction of ScFv Gene Displayed on the Surface of Phage 大鼠抗汉滩病毒单抗可变区基因的克隆、测序和人&大鼠嵌合抗体的表达及ScFv基因构建的研究