Conclusion High level gene expression in mouse liver can be achieved after tail vein hydrodynamic injections of liposome-encapsulated plasmid DNA, and this technique has great potential for a wide variety of gene therapy studies. 结论应用尾静脉高压注射脂质体/质粒DNA复合物途径,目的基因在小鼠肝脏获得高效表达,该方法可以广泛应用于基因治疗的实验研究。
The staple carrier system includes viral carriers such as retrovirus, adenovirus, gland-related virus and non-viral-carriers such as lipidosome, bare DNA or diversified particulates. The early gene therapy studies used to make retrovirus as a carrier. 目前常用的基因治疗载体系统有逆转录病毒、腺病毒、腺相关病毒等病毒载体,以及脂质体、裸DNA、各种微粒或聚合物包裹等非病毒载体系统。
Thank you so much for what you said about this treatment, that therapy, those studies. 非常感谢您宣讲了关于这种治疗、疗法或研究的信息。