The aim of this study was to define the changes of cellular trace element concentration during the carcinogenesis process of Wistar rat palatine mucosa squamous epithelial cell induced by 4 nitroquinoline 1 oxide ( 4NQO ). 目的:研究4硝基喹啉氧化物(4nitroquinoline1oxide,4NQO)诱发大鼠腭粘膜上皮细胞癌变过程中细胞内微量元素的变化及意义。