AIM : To study the changes in the expression and phosphorylation of cAMP response element binding protein ( CREB ) in the rat nucleus accumbens after chronic ethanol intake and its withdrawal. 目的:研究慢性酒精摄取和戒断后大鼠伏核内cAMP反应元件结合蛋白(CREB)表达和磷酸化的变化。
CAMP response element binding protein ( CREB ) was one of the most important transcription factor, which had important effect on learning-memory. 环磷酸腺苷反应元件结合蛋白(CREB)作为一种重要的核转录因子,在学习记忆中有着重要的作用。
Phosphorylation of cAMP response element binding protein in glioma cells induced by bradykinin 缓激肽诱导胶质瘤细胞内cAMP反应元件结合蛋白磷酸化的实验研究
AIM : In order to explore the role of activator protein-1 ( AP-1 ) and cAMP response element binding protein ( CREB ) in acute lung injury and anti-inflammatory mechanism of glucocorticoid. 目的探讨活化蛋白-1(AP-1)和cAMP反应元件结合蛋白(CREB)在急性肺损伤(ALI)发生发展中的可能作用,以及地塞米松的抗炎作用机制。
CAMP response element-binding ( CREB ) proteins are a family of mammalian transcription activators that mediate cAMP and calcium-dependent gene expression through the cAMP response element ( CRE ). cAMP反应元件结合蛋白(cAMPresponseelement-BindingProteins,CREB)是一个哺乳动物转录因子家族,通过cAMP反应元件(cAMPresponseelement,CRE)调节cAMP和钙离子依赖性基因的表达。