These data suggested that alb-Cre-ERt expression vector was constructed successfully, and 4-OHT could induce Cre-mediated recombination only in hepatocytes expressing Cre-ERt, thereby activating a stably integrated hAP reporter gene. 这些结果表明已成功构建肝细胞特异表达AlbCreERt载体,并在表达Cre融合蛋白的BRL细胞证实4OHT能够诱导Cre介导的DNA重组,从而激活碱性磷酸酶报告基因的表达。