Obtaining differentially expressed genes dynamically and high throughput during the development of pancreatic cancer by application of the expression of rat whole genome microarrays. 3. 应用大鼠全基因组的表达谱芯片,高通量、动态地筛选出胰腺癌发生及发展过程中差异表达的基因。
Application of high throughput screening in drug development 高通量药物筛选在新药研究中的应用
For the laborious testing, huge investment, low sensitivity and the requirement of many animals, traditional toxicological experiments can hardly satisfy the need of high throughput screening in nowaday drug development. It is in very urgent need to develop new methods for toxicity evaluation. 传统的用于药物毒性评价的常规毒理学实验方法因周期长、耗资多、灵敏度低、需消耗大量实验动物等缺陷而难以满足现代药物开发中进行高通量筛选的需求,亟待发展新的毒性评价方法。
High Throughput Separation and Identification for Proteomics and Recent Development in Proteome APPLICATION AND ADVANCES OF SEPARATION METHODS FOR PROTEOMICS 蛋白质组的分离与分析及其应用进展蛋白质组分离方法及其进展
Application of new techniques such as biochip, combinatorial chemistry, combinatorial biosynthesis computer etc in high throughput screening, has been promoted the procedure of new drug development. 高通量药物筛选技术的快速发展,促进了高新技术和科学研究成果在医药科学研究中的广泛应用。