Increasing the confidence level to 99 per cent reduced the group to 11 but also reduced the false discovery rate to 22 per cent, meaning only two or three funds had been wrongly selected. 置信度增加至99%,区间范围减少至11,但也将错误发现率(FDR)减少至了22%,意味着仅有两三只基金被选错。
Objective To apply false discovery rate ( FDR ) and its several control procedures for microarray data. 目的介绍阳性结果错误率(FDR)及相关控制方法在微阵列数据多重比较中的应用。
This paper reports a method to threshold the statistical parametric map of fMRI, which combines controlling the false discovery rate with analyzing the spatial correlation of the cortical hemodynamic responses. 为此提出了一种组合控制错误发现率(FDR)及分析皮层血流动力学响应的空间相关性阈值化功能磁共振统计参数映射图的方法。
Firstly, for identifying the active voxels, the proposed method determines threshold based on controlling false discovery rate. Secondly, it analyzes and tests the correlation of hemodynamic responses between the identified active voxels and their 26-neighboring voxels. 该方法首先采用基于控制错误发现率(FDR)的方法确定阈值,进行激发体素判别,然后分析已判别为激发的体素与其三维空间26-邻域体素的血流动力学响应的相关性,并进行空间相关检验。
An F-statistic based Henderson method III was constructed to test the significance of differential expression for each gene under different treatment ( s ) levels. The cutoff P-value was adjusted to control the experimental-wise false discovery rate. 采用基于Henderson方法Ⅲ的F统计量来检验每个基因在不同处理水平下的表达差异,并通过调整P值的阈值来控制试验水平的假发现率。