Detection of peripheral blood lymphocyte subsets in treated syphilis patients with persistent positivity for rapid plasma reagin 梅毒血浆反应素快速试验持续阳性患者外周血淋巴细胞亚群的检测及其临床意义
Objective To observe the changes in peripheral blood lymphocyte subsets in patients with latent syphilis aftertreatment, who had persistent positive results of test for rapid plasma reagin ( RPR ) and remained infectious. 目的观察经驱梅治疗后梅毒血浆反应素快速试验(RPR)持续阳性且仍具传染性的隐性梅毒患者外周血淋巴细胞亚群的变化。
Methods Serological ELISA was conducted twice to determine HIV antibodies in serum and positive samples during the first round of screening was sent to CDC for identification; rapid plasma reagin circle card test ( RPR ) was used once to detect syphilis antibodies in serum. 方法采用2次血清酶联免疫吸附试验的方法,检测血清中HIV抗体,初筛阳性标本送省疾病预防控制中心确认,采用1次快速血浆反应素环状卡片检测血清中梅毒抗体。
Results : 26 infants with asymptomatic congenital syphilis all had the positive antibody of syphilis by treponema pallidum agglutination Assay ( TPPA ), their titres were higher 4 folds than their mother's, and 8 infants complicated with positive rapid plasma reagin circle card test ( RPR ). 结果26例无症状先天性梅毒患儿血清梅毒螺旋体血球凝集试验(TPPA)全部阳性,滴度高于他们的母亲4倍以上,有8例患儿同时伴梅毒快速血浆反应素环状卡片试验(RPR)阳性。
Fluorescent treponemal antibody absorption ( FTA-ABS ) test and rapid plasma reagin ( RPR ) test were of the highest specificity among the serologic tests. 荧光螺旋体抗体吸收(FTA-ABS)试验及梅毒快速血浆反应素试验(RPR)阳性率极高;