No patient had a drug-related serious adverse event or discontinued because of toxicity. 没有患者出现药物相关的严重副作用或因为药物毒性中断治疗。
The only serious adverse event was seen in a patient in the quinine group who developed fatal black water fever. 唯一的严重不利事件是奎宁组中有一名患者罹患了致命的黑尿热。
As well, no definitive serious adverse event reports of distant spread of toxin effect have been associated with Botox when used at approved doses for eyelid twitches or for crossed eyes. 并且,当使用Botox已批准的剂量用于治疗眼皮痉挛或“斗鸡眼”(crossedeyes)时亦未见因毒素作用远端扩散而导致的最终严重不良事件(SAE)报道。