Objective : To study the possibility and efficacy of high dose chemotherapy with autologous peripheral blood progenitor cell transplantation in the treatment of high risk solid tumors, and to study the issues of stem cell mobilization, harvest timing and bone marrow engraftment. 目的:探讨高剂量化疗并自体外周血干细胞移植治疗高危实体瘤的可行性及疗效并了解干细胞动员、采集时机、骨髓恢复时间等问题。